Iman Emam
Associate Professor

Bio

Dr. Iman holds a Ph.D. degree conducted at Technical University in Munich (Klinikum rechts der Isar), Germany, with research interest directed towards molecular oncology and dedicated to both basic sciences to better understand the tumor biology, in addition to applied research to improve early diagnosis and prognosis for cancer treatment. She has around 20 Publications in peer-reviewed journals, 11 conference publications, 3 book chapters and a world-wide patent. She participated in 22 national and international conferences, and she is contributing at peer-reviewing activities in more than 11 international journals.

Qualifications

  • B.Sc. Science, Biology, Cairo University.
  • M.Sc. Copenhagen University (Panum Institute), Denmark & Cairo University.
  • Ph.D. Technical University in Munich (Klinikum rechts der Isar), Germany & Ain Shams University.
  • Post doctorate Mount Sinai School of Medicine, NewYork, USA.
  • Post doctorate Pierre et Marie Curie University, ParisVI – Currently Sorbonne, (L’Hopital Salpetrier Medical School), Paris, France.

Area of Research

  • Molecular Oncology
  • Genomics
  • Proteomics
  • Stem Cells Biology
  • Gene Therapy
  • Classical and Molecular Cytogenetics & Nanotechnology

List of Publications

– Journal Publications

  1. Aya Ahmed Sebak, Iman Emam Omar Gomaa, Aliaa Nabil ElMeshad, Mahmoud Hussien Farag, Ulrike Breitinger, Hans-Georg Breitinger and Mahmoud Hashem Abdel Kader (2020). Distinct Proteins in Protein Corona of Nanoparticles Represent a Promising Venue for Endogenous Targeting – Part II: In vitro and in vivo kinetics study. Int. J. Nano Med; 15: 9539–9556.
  2. Aya Ahmed Sebak, Iman Emam Omar Gomaa, Aliaa Nabil ElMeshad, Mahmoud Hussien Farag, Ulrike Breitinger, Hans-Georg Breitinger and Mahmoud Hashem Abdel Kader (2020). Distinct Proteins in Protein Corona of Nanoparticles Represent a Promising Venue for Endogenous Targeting – Part I: In vitro Release and Intracellular Uptake Perspective. Int. J. Nano Med; 15: 8845–8862.
  3. Soad Nasr, Mai Rady, Aya Sebak, Iman Gomaa, Walid Fayad, Menna El Gaafary, Mahmoud Abdel‐Kader, Tatiana Syrovets, and Thomas Simmet
    (2020). A Naturally Derived Carrier for Photodynamic Treatment of Squamous Cell Carcinoma: In Vitro and In Vivo Models. Pharmaceutics.
    12: 494 – 509.
  4. Soad Nasr, Mai Rady, Iman Gomaa, Tatiana Syrovet, Thomas Simmet, Walid Fayad, Mahmoud Abdel-Kader (2019). Ethosomes and lipid-coated chitosan nanocarriers for skin delivery of a chlorophyll derivative: A potential treatment of squamous cell carcinoma by photodynamic therapy. Int. J. Pharmaceutics. 568: 118528
  5. Mai Rady, Iman Gomaa; Nagia Afifi; Mahmoud Abdel-Kader (2018). Dermal Delivery of Fe-Chlorophyllin via Ultradeformable Nanovesicles
    for Photodynamic Therapy in Melanoma Animal Model. Int. J. Pharmaceutics. 548: 480-490.
  6. Aya Sebak, Iman Gomaa, Aliaa El-Meshad, Mahmoud Abdel-Kader (2018). Targeted Photodynamic-Induced Singlet Oxygen Production by
    Peptide Conjugated Biodegradable Nanoparticles for Treatment of Skin Melanoma. Photodiagnosis and Photodynamic Therapy; 23: 181-189.
  7. Aya Shoukry Sayed, Iman Gomaa, Michael Bader, Nesrine Salah El Dine El Sayed (2017). Role of 3-Acetyl-11-Keto-Beta-Boswellic Acid in
    Counteracting LPS-Induced Neuro-inflammation via Modulation of miRNA- 155. Mol. Neur. Journal. (2018) 55: 5798 – 5808.
  8. Iman Gomaa; Aya Sebak; Nagia Afifi, Mahmoud Abdel-Kader (2017). Liposomal Delivery of Ferrous Chlorophyllin: A Novel Third
    Generation Photosensitizer for in vitro PDT of Melanoma. Photodiagnosis and Photodynamic Therapy; 18: 162-170.
  9. Mahmoud Elfar; Mariam Ayoub; Aya Sameh; Hazem Abass; Reham M. Abdel- Kader; Iman Gomaa and Islam S. M. Khalil (2016). Targeted
    Penetration of MCF-7 Cells using Iron-Oxide Nano-Particles In Vitro (ICRA).
  10. Riham F. George; Marwa A. Fouad, and Iman E.O. Gomaa (2016). Synthesis and Cytotoxic Activities of Novel Pyrazoline Derivatives
    Bearing Phenyl Pyridazine Core. Europ. J. Medicinal Chemistry. 112: 48 – 59.
  11.  MF Mohamed; HA El Deeb; and IE Gomaa, and EH Mobarak (2015). Bond Durability of Different Resin Cements to Caries-Affected Dentin Under Simulated Intrapulpal Pressure. J. Operative Dentistry. 40- 51.
  12. Gomaa I.E.; Bhatt S.; Liehr T.; Glei M., and El-Tayeb T.A. (2015). “Comparative in vitro study of Ag and Co/Ag nanoparticles mediated photothermal therapy of cancer”. Egypt. J. Zool. 63: 99 – 118.
  13. Iman E. Gomaa, Sara A. Abdel Gaber, Samarth Bhatt, Thomas Liehr, Michael Glei, Tarek A. El-Tayeb, Mahmoud H. Abdel-Kader (2015). “In vitro cytotoxicity and genotoxicity studies of gold nanoparticles-mediated photo-thermal therapy versus 5-fluorouracil". Journal of Nanoparticle Research. 17(2); 17:102
  14. Worldwide patent (2011): Cobalt/Silver core shell nanoparticles application in solid tumour treatment. Date: 07/03/2010 Application No.:
    PCT/EG2010/000009 Inventors: Assoc. Prof. Dr. Tarek Abd Allah ElTayeb, Ass. Prof. Iman Omar Gomaa Assoc. Prof. Mona Mohamed Bakr.
    Mr. Mohamed Ahmad Ghaly & Mrs. Marwa Ali Ramadan. Institutions; Faculty of Pharmacy and Biotechnology. German University in Cairo &
    The National Institute for Laser Enhanced Sciences. Cairo University, Cairo, Egypt.
  15. Iman Emam Omar Gomaa, Mahmoud Hashem Abdel Kader, Taher Ahmed Salah, Ola Ahmed Heikal (2013). Evaluation of in vitro Mutagenicity and Genotoxicity of Magnetite Nanoparticles. Drug Discovery and Therapeutics. 7(3):116-123
  16. Ara Parlakian, Iman Gomaa, Sounkary Solly, Ludovic Arandel, Alka Mahale, Gustav Born, Giovanna Marazzi, David Sassoon (2010). Skeletal
    Muscle Phenotypically Converts and Selectively Inhibits Metastatic Cells in Mice. PLoS ONE. 5(2): 1-14. Anton M, Gomaa IE, von Lukowicz T, Molls M, Gansbacher B, Wurschmidt F. (2005). Optimization of radiation-controlled gene expression by adenoviral vectors in vitro. Cancer Gene Ther. Jul;12(7):640-6.

– Book Chapters Publications:

  1. Iman E. Gomaa; Samarth Bhatt, Thomas Liehr, Mona Bakr, and Tarek El-Tayeb (2015). Ag and Co/Ag nanoparticles cytotoxicity and
    genotoxicity study of HEp-2 and bloof lymphocytes. In: Chemical Technology – Key Developments in Applied Chemistry, Biochemistry,
    and Materials Sceicne. Edit. Nekane Guarrotxena; Gennady E. Zaikov; and A.K. Haghi. Apple Academic Press Inc. & CRC Press.13-29.
  2. Iman Gomaa; Samarth Bhatt; Thomas Liehr; Mona Bakr and Tarek A. El-Tayeb (2015). A Study on Biological Application of Ag and Co/Ag
    nanoparticles cytotoxicity and genotoxicity. In: Nanomaterials and Nanotechnology for Composites – Design, Simulation and Applications. Edit. AK Hagi; Sabu Thomas; Ali Pourhashemi, Abbas Hamrang and Ewa Klodzinsk. Apple Academic Press Inc. 139 – 153.
  3. Islam SM Khalil; Iman EO Gomaa; Reham M Abdel-Kader and Sarthak Misra (2015). Magnetic – Based contact and non-contact manipulation of cell mockups and MCF7 human breast cancer cells. In: Smart Drug Delivery System. ISBN: 978-953-51-4588-2. In Tech
    Europe.

Conference Publications

  1. An Investigation of the Sensing Capabilities of Magnetotactic Bacteria. Nermeen S. El-Din, Mohamed Ewis, Noura Yousry, Ola Ahmed, Iman
    Gomaa, Anke Klingner, Tijmen Hagemanz, Marc Pichelz, Mohamed E. Mitwally, Leon Abelmannzx, and Islam S. M. Khalil. IEEE. Engineering in July 17-21, 2018.
  2. Iman Gomaa, Mohamed Ghaly, Marwa Ramadan, Mona Bakr, Tarek A. El-Tayeb (2012). In vitro and in vivo photothermal therapy of cancer using laser enhanced Ag and Co/Ag nanoparticles”. Nano-Bio Collaborative International Conference. Tampa, Florida, USA.
  3. Iman Gomaa, Sara E. Ali, Tarek A. El-Tayeb, Mahmoud H. Abdelkader. Chlorophyll derivative mediated PDT versus methotrexate for
    breast cancer treatment. Journal of Photodiagnosis and Photodynamic Therapy, 2012; 9(4): 287-384.
  4. Iman Gomaa, Sara E. Ali, Tarek A. El-Tayeb, Mahmoud H. Abdelkader. Chlorophyll derivative mediated PDT versus methotrexate for breast cancer treatment. The first International Conference of Photodynamic and Nanomedicine for Cancer Diagnosis and Therapy (ICPN), Cairo, Egypt, Feb. 2012.
  5. Iman Gomaa, Gustav Born, Giovanna Marazzi, David Sassoon. Molecular and cellular factors underlying the rarity of secondary tumour
    metastasis in skeletal muscles The International Conference for Molecular and Cellular Oncology (ICMCO), Egypt. Feb. 2010.
  6. Iman Gomaa, Giovanna Marazzi, David Sassoon. Muscletumorinteractionsandhidden stem cells. Lucca (Barga), Italy. May 2007.
  7. ‘I. E.O. Gomaa, M. Anton, T. v. Lukowicz, M. Molls, B. Gänsbacher, and F. Würschmidt. Gene Expression Under the Control of the Radiation Inducible Egr-1 Promoter in an Adenoviral Vector: Vector Optimization For Reduction of Unspecific Gene Expression in the Absence of
    Irradiation’, (Proceedings of the International 6th. Wolfsberg Meeting on Molecular Radiation Biology / Oncology, 2002, Vol. 3, S.96).
  8. Iman E.O. Gomaa, Martina Anton, Tobias von Lukowicz, Michael Molls, Bernd Gänsbacher & Florian Würschmidt. ‘Gene Expression
    Under Control of the Radiation- Inducible Egr-1 Promoter in an Adenoviral Vector: Vector Optimization for Reduction of Unspecific
    Gene Expression in the Absence of Irradiation’. African Radiation Oncology Group. Proceedings of AFROGII, Abstract: G8, S. 20.
  9. F. Würschmidt, I.E.O. Gomaa, M. Anton, T. v. Lukowicz, M. Molls, and B. Gänsbacher. Gene expression under control of the radiation
    inducible Egr- 1 promoter: Optimization of Ad-vector for reduction of unspecific gene expression in the absence of irradiation’ at the “Proceedings of the 10th International Conference on Gene Therapy of Cancer, San Diego, USA“ (Dec 12th – Dec 15th 2001). (J. ISCGT, 2001, Vol. 8, Suppl. 2, Abst. No. 112 late).
  10. Würschmidt F, Gomaa IEO, Anton M, v. Lukowicz T, Gänsbacher B, Molls M. ‘Gene expression under control of the radiation-inducible Egr-1 promoter in an adenoviral vector: Strategies of Vector Optimization’. At the European Cancer Conference (ECCO/ESTRO) Congress. Lisboa, Oct. 2001. Eur. J. Cancer, Vol. 37 (Suppl. 6); S. 160. I.E.O.Gomaa, M. Anton, T.v. Lukowicz, B. Gänsbacher, M. Molls, and F.Würschmidt. at 11 by adenoviral vectors’. AEK Congress, 2001 Symposium of the “Arbeitsgemeinschaft Experimentelle Krebsforschung” of the “Deutsche Krebsgesellschaft” in Heidelberg, Germany. (J. Cancer Res. Clin. Oncol. 2001, Vol. 127 (Suppl. 1); S. 76).

– Conference Presentations

  1. Pharmacists in Frontlines; New Challenges and Innovative Solutions Online oral presentation; Cairo, Egypt, December, 2020
  2. The second International Conference on Pharm-Science Research & Development. Invited speaker; Los Angeles, USA, February, 2020
  3. World Structural and Molecular Biology Conference. Invited speaker; Rome, Italy, November, 2018
  4. International Conference of the Faculty of Pharmacy, Ain Shams University. Invited speaker; Cairo, Egypt, November, 2018
  5. Cell Science International Conference Key note speakers; Potential Cellular and Molecular Mechanisms underlying the rarity of metastasis in skeletal muscles Invited speaker; Chlorophyllin Derivatives Mediated PDT of Cancer; In vitro and In Vivo Approaches for Targeted Therapy. Dubai, UAE, April, 2017
  6. Era of Gene Therapy Invited Speaker; Local tumour therapy with an adenoviral vector containing a gene under the control of a radiation inducible promoter. NRC, Cairo, Egypt. February, 2017
  7. The 9th. International Conference on Laser Applications (ICLA9) Invited speaker; “Attempts for laser assisted PDT; In vitro and in vivo cancer therapy. National Laser Institute, Cairo University, Cairo, Egypt, November, 2016.
  8. The World Biotechnology Conference Invited speaker; Chlorophyllin Derivatives Mediated PDT: A New Ray of Hope in the Horizon for Cancer Treatment, Sao Paulo, Brazil, August, 2016.
  9. The “Biotechnology Day”. Biotechnology Department, Faculty of Science, Cairo University, 18th. July Invited speaker; Chlorophyllin Derivatives Mediated PDT: A New Ray of Hope in the Horizon for Cancer Treatment Evaluator for the Biotechnology graduation projects competition at the same event ** Awarded “The Shield of Honor of the Faculty of Science- Cairo University”
  10. “In-Vitro Protocols for Anticancer Drugs”, sponsored by STDF & Academy of Scientific Research. Invited speaker; Potential Cellular and Molecular Mechanisms underlying the rarity of metastasis in skeletal muscles. National Research Center, Cairo – Egypt. 25th. August
  11. International Society for Optics and Photonics (SPIE): Poster presentation; In Vivo Suppression of Solid Ehrlich Cancer via Chlorophyllin Derivative Mediated PDT: An Albino Mouse Tumour Model. San Francisco, California, USA, February, 2015.
  12. ICPN, 2015: International Conference for Photodynamic and Nanotechnology Oral Presentation; Chlorophyllin Derivatives Mediated PDT: A New Ray of Hope in the Horizon for Cancer Treatment. Cairo, Egypt, January. 2015.
  13. International Conference for Holistic Medicine (ICHM): Oral Presentation; “In vivo photothermal therapy of cancer using laser enhanced Ag and Co/Ag nanoparticles”. Kottayam, Kerala, India. September, 2013.
    7. Nano-Bio Collaborative International Conference: Poster presentation; “In vitro and in vivo photothermal therapy of cancer using laser enhanced Ag and Co/Ag nanoparticles”. Tampa, Florida, USA. March (22–24. 2012).
  14. ICPN, 2012: International Conference for Photodynamic and Nanotechnology Oral presentation; “Chlorophyll derivative mediated PDT versus methotrexate for breast cancer treatment”. The first International Conference of Photodynamic and Nanomedicine for Cancer
    Diagnosis and Therapy, Cairo, Egypt, Feb. 2012.
  15. ICMCO Congress: Oral Presentation; “Molecular and cellular factors underlying the rarity of secondary tumor metastasis in skeletal muscles”. The first International Conference for Molecular and Cellular Oncology, Cairo, Egypt. Feb. 2010.
  16. EUROTOX Congress: Poster presentation; The 46 . Congress of the European Society of Toxicology. Dresden, Germany 2009
  17. Gordon Research Conference: Oral Presentation; Muscle-tumor interactions and hidden stem cells. Lucca (Barga), Italy. May 2007.
  18. AFROGII Congress: Oral presentation; at The African Radiation Oncology GroupII, Cairo, Egypt, Dec. 2003.
  19. Wolfsberg Meeting: Poster presentation; at the Wolfsberg Meeting for Molecular Radiation Biology & Medicine, Switzerland, June 2002.
  20. International conference for Cancer Gene Therapy:
  21. The AEK congress: Poster presentation; at the Radiation Oncology Congress organised by the German Cancer Institute, Heidelberg, Germany, April 2001.

Job Grades

  • Teaching Assistant, March, 1997
  • Assistant Lecturer,  May, 2000
  • Lecturer,  February, 2005
  • Associate Professor,  January, 2016

Activities

Academic & Technical Expertise

  1. Developing undergraduate PharmD. Curriculum (designing and implementation of a Biomedical Sciences sector in the Pharmacy School, MSA University).
  2. Developing undergraduate Biotechnology curriculum and bylaws (B.Sc. in Biotechnology for the already functional Biotechnology School) at Nile University.
  3. Developing postgraduate Nanotechnology curriculum and bylaws [(A joint M.Sc. program in Nano-science and Technology between Centre of Nanotechnology (CNT) – Nile University, and Egypt Nanotechnology Centre (EGNC) – Cairo University].
  4. Establishing Life Sciences laboratories (Molecular Biology, Mammalian Cell Culture, Microscopy units).
  5. Writing up both national and international research grant (Ex: CSSP, STDF, DAAD), in addition to capacity building grants (Ex: ERASMUS – KA2).
  6. Deep experience in the following molecular techniques; DNA Cloning, Production and purification of plasmid and viral vectors as gene delivery systems, Gene Transfection, Gene transduction, PCR (quantitative & conventional), Blotting techniques (Western, Southern, Northern, Dot blot), Genotyping, ELISA, In situ hybridization, Cell sorting (FACS), Histological techniques (Conventional Histopathology, & Immunohistochemistry), Cell Culture techniques (Cell lines, Primary cells, Stem cells), Microscopy (Light, Fluorescence & Confocal). Establishment and treatment of tumour animal models.
  7. Construction and designing undergraduate Biotechnology curriculum.

  8.  Construction and designing postgraduate Nanotechnology curriculum.

Peer-Review Activities

  1. Reviewer at “Center for Specialized Studies and Research Programs / CSSP” – “La Bibliotheca Alexandrina”.
  2. Reviewer of DAAD GERSS / GERLS scholarship.
  3. Reviewer at STDF – ASRT
  4. Reviewer at Journal of nanoparticle Research.
  5. Reviewer at Journal of Advanced Research.
  6. Reviewer at Food and Chemical Toxicology Journal.
  7. Editorial member of Pharmacology United prime pub Journal.
  8. Editorial member of Scientific Journal of Pharmacy & Pharmaceutical Sciences (AJPPS)
  9. Editorial member of the American Journal of Bioscience.
  10. Editorial member of the American journal of Pharmacology.
  11. Associate Editor in Chief for the “Arabian Journal of Medical Sciences".
  12. Examiner of Postgraduates at GUC & Biotechnology graduates at Cairo University.

Additional Activities

  1. Member of the Institutional Animal Care and Use Committee (IACUC) – Medical Sciences Sector, Cairo University.
  2. Active alumni member of Technische Universität München (TUM) – both at head office (München) & Das Deutsche Wissenschaftliche Zentrum (DWZ) – DAAD Kairo office.
  3. Active board member of DAAD Alumni Verein (DAV).
  4. Active alumni member at DAAD – Cairo office.
  5. Consultant at establishment of mammalian cell culture laboratory at National Institute for Laser Enhanced Sciences (NILES) – Cairo University.
  6. Scientific and technical consultation at the establishment of the cell culture laboratory facility at the Pharmacognosy Department – Faculty of Pharmacy, Cairo University.
  7. Head of “Egy-TUM Alumni” – Egyptian alumni of Technical University of Munich.
  8. General Secretary of “The Tree of Hope” – Charity Foundation.

Awards & Honorable Mentions

  • EUC – MSc. Scholarship (1996 – 1998) Copenhagen University – Faculty of Medicine – Protein Laboratory.
  • DAAD – Ph.D. Scholarship (2002 – 2003) Technical University of Munich – Faculty of Medicine – Experimental Oncology Department & Radiotherapy Clinic.
  • Postdoctoral Scholarship (2004 – 2005) Mount Sinai School of Medicine – Cell, Molecular and Developmental Biology Department Postdoctoral Scholarship (2005 – 2007) University of Piere et Marie Curie -– Faculty of Medicine – Myology Institute.
  • DAAD Postdoctoral Scholarship (2010) University of Jena -– Faculty of Medicine – Institute of Human Genetics and Anthropology.
  • DAAD Postdoctoral Scholarship (2012) Technical University of Munich -– Faculty of Medicine Faculty of Medicine – Experimental Oncology Department & Radiotherapy Clinic.

Projects

  • National Research Grant: Principle investigator of STDF grant no. 26334 of 1.000.000 LE Academy of Scientific Research and Technology.
  • National Research Grant: Principle investigator of CSSP research grant no. 145 of 63.000 LE ($ 12000). The Centre for special studies and programs (CSSP). La Bibliotheca Alexandrina. Egypt.
  • International patent: Cobalt/Silver core shell nanoparticles application in solid tumour treatment. WO 2011/110186 A1
  • International Research Grant: Member, RDI – project Number C2/S1. Topic: Development of Rice Bran Nutraceuticals EU Egypt Innovation Fund Rice Bran Nutraceuticals.
  • DAAD Equipment grant: Principle investigator. Research equipment grant from the German Academic Exchange Services. Grant no. ga43213 of (20,000 Euros). 

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